Differential G-protein-coupled Receptor Phosphorylation Provides Evidence for a Signaling Bar Code
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Differential G-protein-coupled Receptor Phosphorylation Provides Evidence for a Signaling Bar Code*
G-protein-coupled receptors are hyper-phosphorylated in a process that controls receptor coupling to downstream signaling pathways. The pattern of receptor phosphorylation has been proposed to generate a "bar code" that can be varied in a tissue-specific manner to direct physiologically relevant receptor signaling. If such a mechanism existed, receptors would be expected to be phosphorylated in...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2011
ISSN: 0021-9258
DOI: 10.1074/jbc.m110.154526